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So We’ve Known All Along That Coronavirus Vaccines Are Very Dangerous | “Immunization With SARS Coronavirus Vaccines Leads To Pulmonary Immunopathology On Challenge With The SARS Virus” | NIH

2012;7(4):e35421. doi: 10.1371/journal.pone.0035421. Epub 2012 Apr 20.

Researchers: Chien-Te Tseng 1Elena SbranaNaoko Iwata-YoshikawaPatrick C NewmanTania GarronRobert L AtmarClarence J PetersRobert B Couch

Background:Severe acute respiratory syndrome (SARS) emerged in China in 2002 and spread to other countries before brought under control. Because of a concern for reemergence or a deliberate release of the SARS coronavirus, vaccine development was initiated. Evaluations of an inactivated whole virus vaccine in ferrets and nonhuman primates and a virus-like-particle vaccine in mice induced protection against infection but challenged animals exhibited an immunopathologic-type lung disease.

Conclusion: These SARS-CoV vaccines all induced antibody and protection against infection with SARS-CoV. However, challenge of mice given any of the vaccines led to occurrence of Th2-type immunopathology suggesting hypersensitivity to SARS-CoV components was induced. Caution in proceeding to application of a SARS-CoV vaccine in humans is indicated.

[Full Article At National Institutes Of Health]

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